Polynucleotides
in Whitley Bay.
DNA-based bio-stimulation. Under-eyes. Texture. Long-term skin quality.
What to expect.
Polynucleotides are regenerative injections from salmon DNA. They wake up your fibroblasts. Those cells then make collagen and elastin. Excellent for under-eye hollowing, skin laxity and long-term quality.
Areas we treat: Under-eyes · Texture · Laxity
Three steps.
What it costs.
Polynucleotides are priced by area. Most clients start with eyes (the area most clinics won’t put filler in). Then they build to face if they want skin-quality improvement everywhere.
| Treatment | Per session | |
|---|---|---|
| Eyes (under-eye, tear-trough region). 45 mins | £185 | Book |
| Face. 45 mins | £210 | Book |
| Face + neck. 60 mins | £250 | Book |
Best results come from three sessions, three weeks apart. We agree the protocol at consultation. Free 30-minute consultation if you’re new.
What they actually do.
Polynucleotides are short, purified DNA fragments. Usually from salmon roe. Highly purified. No allergenic protein. They’re a regenerative injectable. Not a filler. They don’t add volume or change your features.
I inject them into the layer just below your skin. They switch on the cells (fibroblasts) that make collagen, elastin and hyaluronic acid. They wake up cells that have been sleeping. The result builds slowly. Skin gets thicker, denser, better quality. Lines soften because the skin is healthier. Not because something has been filled in.
Polynucleotides shine in the under-eye. The skin there is the thinnest on the face. The area most prone to dark circles, hollowness and crepiness as we age. Filler under the eye is risky. It’s a tight space. Blood vessels are close. Then there’s the dreaded Tyndall effect (a bluish tint when filler sits too superficially). Polynucleotides give us a way to improve under-eye quality without those risks.
Other places they earn their keep: scarred skin, sun-damaged skin, skin that’s lost density after weight loss or pregnancy. And the neck and décolleté where filler isn’t usually right.
Who this is for.
Polynucleotides suit you if you:
- Have under-eye hollowness, darkness or crepiness and want improvement without filler
- Want skin quality improvement that builds gradually rather than instantly
- Have sun-damaged or scarred skin that needs cellular-level regeneration
- Are willing to commit to a course of 3 sessions for proper results
- Are 18+, not pregnant or breastfeeding
I’ll recommend something else if you:
- Want immediate volume restoration. That’s filler, not polynucleotides
- Have a fish allergy (rare with this product but worth checking)
- Are pregnant or breastfeeding
- Have an active autoimmune flare
From door to done.
Numbing cream goes on for 15 minutes. Especially important for the under-eye area. The skin there is more sensitive. While we wait, we run through the plan again. You’ll know exactly what we’re doing.
For under-eye, I work in small precise points just below the lash line. For face, micro-droplets across cheeks and jawline. For neck, a longer linear technique. Whole appointment is around 45 minutes including numbing.
Bruising is common in the under-eye area. The skin is thin and vascular. Plan for visible bruising for up to a week. Mild swelling for 24 hours. The result builds across 3 to 12 weeks. You usually notice the change after the second session.
The first 48 hours.
- Cool compresses (not ice directly) for the first few hours
- Don’t rub or massage the treated area for 24 hours
- No alcohol for 24 hours
- No strenuous exercise or saunas for 24 hours
- No facials, peels, microneedling or laser for 14 days
- SPF on the area daily. Sun damage undoes the work you’ve invested in
- Sleep elevated the first night to reduce under-eye swelling
- Bruising can take 7-10 days to fully resolve. Arnica gel helps
What I tell everyone.
Common: bruising. Especially under-eye. Can last 7 to 10 days. Small papules at injection points (settle within 24 to 48 hours). Mild redness. Occasional brief tenderness.
Rare: allergic reaction. The product is highly purified. Allergy testing isn’t usually required. Infection at injection points (good aftercare prevents this).
NMC-registered. Fully indemnified. On the regulators’ lists at NMC, Save Face and JCCP.
Good to know.
Are polynucleotides safe?
Are they made from salmon?
Will I see under-eye improvement?
How is this different from skin boosters?
How is this different from tear-trough filler?
How many sessions do I need?
How long do results last?
Will I bruise under my eyes?
Does it hurt?
Can I have it if I’m pregnant or breastfeeding?
Book your polynucleotides.
Choose your option and pick a time — booked online in under a minute.
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From the journal.
Polynucleotides, explained →Across the North East.
Clients travel from across the North East for polynucleotides at Refined. Pick your town below for the drive, parking and local questions.