Polynucleotides for Newcastle

Poly­nucleotides
in Newcastle.

DNA-based regenerative injections. Under-eye hollowness. Skin quality. Long-term cellular improvement. Not filler. Not volume. Regeneration from inside the tissue.

This page is for clients in Newcastle upon Tyne (NE1, NE2, NE3). Refined is in Seaton Delaval, 8 miles north. About 25 minutes via the A189 north out of the city. Free parking at the clinic.

The Tyne Bridge in Newcastle upon Tyne, the city served by Refined Medical Aesthetics.
From
£185
Newcastle to clinic
8 miles · 25 mins
Consultation
FREE 30 mins
Why clients travel

Why Newcastle clients come here.

Polynucleotides are still being adopted slowly by Newcastle city centre clinics. Many stick to filler or skin boosters. Refined has offered polynucleotides for some time. I know the protocol. I know the under-eye anatomy. I know when it’s the right choice and when filler or boosters would serve you better.

Newcastle clients who travel for polynucleotides are often looking for under-eye improvement without the risks of tear-trough filler. Or they want long-term skin quality, not just a hydration hit. The consultation-first model at Refined means we agree the right answer before committing to anything.

The treatment

Polynucleotides, plainly explained.

Polynucleotides are short, purified DNA fragments from salmon roe. Highly purified. No allergenic protein. They are regenerative injections. Not fillers. I inject them into the layer just below your skin. They switch on fibroblasts, the cells that make collagen, elastin and hyaluronic acid. The result builds slowly across weeks.

The under-eye is where they work best. The skin there is the thinnest on the face. Filler under the eye carries real risk. Polynucleotides give us a way to improve under-eye quality without those risks. Dark circles, hollowness, crepiness. Those all improve gradually with a proper course.

Full detail on suitability, protocols, aftercare and risks on the polynucleotides hub page.

Polynucleotide treatment preparation at Refined Medical Aesthetics, Seaton Delaval.
Pricing

What it costs.

TreatmentPer session
Eyes (under-eye, tear-trough region). 45 mins£185
Face. 45 mins£210
Face + neck. 60 mins£250

Best results come from three sessions, three weeks apart. We agree the protocol at consultation. Free 30-minute consultation if you’re new.

From Newcastle

How to find us.

Refined Medical Aesthetics is on Double Row in Seaton Delaval, NE25 0PP. About 8 miles north of Newcastle city centre.

Take the A189 north from Newcastle, the Great North Road heading through Benton. About 25 minutes depending on traffic. Free parking on Double Row right outside. No apps, no meters. Much less stress than city centre parking.

Postcode for sat-nav: NE25 0PP. Look for the Refined sign at the pod garden entrance.

Common questions from Newcastle

Good to know.

How long is the drive from Newcastle city centre?
About 25 minutes via the A189 north. Free parking on Double Row right outside the clinic. No city-centre parking needed.
Is the two-week review included?
Yes. A review is included after each polynucleotide session. We check how the skin is responding and agree the next step in the course. That’s part of the protocol.
Are there not closer polynucleotide clinics in Newcastle?
Some offer polynucleotides in the city. I’d encourage you to ask how long they’ve been offering them and whether they understand the difference between under-eye PDRN and filler. At Refined, I know the anatomy and I know when polynucleotides are the right call and when something else is better. That matters in a treatment this precise.
Can I message on WhatsApp first?
Yes. Message me at wa.me/447583321635. I reply personally. The in-person consultation must happen before any treatment. But I can answer questions by message first.
Ready?

Book a free consultation.

£0 · 30 minutes · Leave with a plan. Not a pressured booking.

Last updated: 20 May 2026