No. 01b · Nurse-led

Advanced
Anti-Wrinkle.

Brow lift, lip flip, bunny lines and masseter slimming — precision protocols for experienced clients.

Nurse Rachel preparing advanced anti-wrinkle injections at Refined Medical Aesthetics, Seaton Delaval
Duration
30–45 mins
Downtime
None
From
£150
The approach

What to expect.

Advanced anti-wrinkle protocols extend the toolkit beyond the three classic areas. Used sparingly, in the right candidate, these techniques lift the brow, soften a gummy smile, and rebalance a heavy jaw — always built on a foundation of the basics working well first.

Areas we treat: Brow lift · Lip flip · Masseter · Bunny lines

How it works

Three steps.

01
Consultation
We start with a conversation about your goals, history and suitability — never a needle.
02
Treatment
Delivered by Rachel with medical precision, using prescription-only products sourced through licensed pharmacies.
03
Two-week review
Included with every appointment. Small tweaks at this review are on the house.
Pricing

What it costs.

Advanced areas vary in price by complexity. Most are at the same fee as a single “classic” area. Masseter, neck and the over-sweating protocol are higher because they use more product and more time.

Treatment Price
Brow lift £150
Lip flip £150
Gummy smile £150
Smokers’ lines (perioral) £150
Soften upper lip lines £150
DOA / downturned smile £150
Pixie nose-tip lift £150
Masseter (jaw slimming) £220
Neck lift / Nefertiti £250
Hyperhidrosis (underarms / hands / feet) £375

All advanced treatments require an in-person consultation first — these aren’t booked off a price list. Two-week review included on every treatment.

The science, plainly

When “advanced” actually means.

Advanced anti-wrinkle protocols use the same medicine as classic anti-wrinkle — botulinum toxin Type A, prescription only — but injected into different muscles for different effects. The technique is more nuanced because the consequences of imprecise placement matter more.

Brow lift targets the depressor muscles around the brow. When those are softened, the elevators win the tug-of-war and the brow sits a few millimetres higher. Subtle, but measurable in photos.

Lip flip places a tiny dose into the orbicularis oris (the muscle that purses the upper lip). The lip relaxes outward, showing more pink. It’s an alternative to filler for clients who want a subtle change without volume.

Gummy smile softens the muscle that lifts the upper lip too high when you smile. The smile shape stays yours; less gum shows.

Masseter (jaw slimming) is one of the highest-impact protocols. Injecting into the masseter muscles softens jaw clenching (great for bruxism / TMJ pain) and gradually slims the jawline appearance over 4-6 weeks. Lasts 4-6 months.

Neck / Nefertiti lift places multiple small doses along the platysma (the band of muscle in the neck) to soften the tug-down on the jawline. Subtle improvement to neck-jaw definition.

Hyperhidrosis is the medical name for excessive sweating. The same medicine, injected into the underarm, hands or feet, blocks the signal to sweat glands for 4-6 months. Genuinely life-changing for people who’ve struggled with this for years.

Suitability

Who this is for.

Advanced protocols suit you if you:

I’ll typically suggest classic anti-wrinkle first if you:

On the day

From door to done.

First time? Mandatory consultation first — advanced protocols aren’t booked off a price list. We talk through what you’re hoping to address, I look at your face in proper lighting, and we agree the protocol.

On treatment day, we go over consent and questionnaire. Numbing cream isn’t typically needed (the injections are tiny), but available if you want it. Each injection is a few seconds. The whole appointment is 30-45 minutes depending on areas treated.

Results start showing day 3-5, peak at day 14. We always do a 2-week review on the house. For masseter and neck specifically, the muscle-thinning effect develops over 4-6 weeks.

Aftercare

The same rules apply.

Risks: brief asymmetry that resolves at the 2-week review, mild headache for a day, pinpoint injection marks. For brow lift specifically, eyelid drop is the rare complication we discuss in detail. Everything resolves fully as the medicine wears off — that’s the safety net.

Common questions

Good to know.

Am I a candidate for advanced protocols?
Usually only if you’ve had classic anti-wrinkle for a while and we know how your face responds to the medicine. Mandatory consultation first — these aren’t treatments to dive into without a proper conversation.
How soon do I see a brow lift?
Subtle lift from week 1, peak at 2 weeks. Lasts roughly 3 months. The lift is millimetres, not centimetres — this is a soft refinement, not a surgical brow lift.
Does masseter slimming hurt?
The injection itself is quick and well-tolerated — the masseter is a deep muscle, so the needle goes in cleanly without much surface sensation. Some clients experience mild jaw fatigue or aching for a few days; it settles.
How long does masseter last?
4-6 months for the muscle-thinning effect. Bruxism / clenching reduction often outlasts the visible slimming. We typically re-treat at 5-6 months.
Will a lip flip make my lips look done?
No — that’s the whole point. A lip flip relaxes the upper lip muscle so a sliver more pink shows when you’re at rest. No volume added. Lasts 6-8 weeks (shorter than classic anti-wrinkle because the muscle is small).
What happens if my brow drops?
Eyelid or brow drop is rare but it’s the named risk for brow-lift treatments. If it happens, it resolves as the medicine wears off — usually within a few weeks. We discuss it in detail at consultation, you sign consent, and I always start conservatively.
How does the hyperhidrosis treatment work?
The same medicine, injected into the area where you sweat (underarms most commonly), blocks the nerve signal to the sweat glands. The effect lasts 4-6 months. For people who’ve struggled with excessive sweating for years, it’s genuinely life-changing.
What about a “Nefertiti” or neck lift?
Multiple small doses along the platysma (the rope-like muscle in the neck) softens the downward tug on the jawline. Best in clients with strong platysmal banding or visible neck cords. It’s subtle — we don’t recommend it as a substitute for surgical lift.
Can I have advanced and classic anti-wrinkle at the same appointment?
Often, yes — that’s how most clients have it. Three classic areas plus a lip flip, or classic plus brow lift. We work it out at consultation.
Can I have it if I’m pregnant or breastfeeding?
No — we’d wait. The principle is to defer non-essential treatments during pregnancy and breastfeeding.
Ready?

Book a consultation.

£0 · 30 minutes · Walk out with a plan, not a pressured booking.

Related treatments

You might also explore.

Also consider
Anti-wrinkle injections
Soft, movement-friendly results.
Also consider
Dermal fillers
Reversible hyaluronic acid, dosed to your features.
Also consider
Book a consultation
Free, 30 minutes — no pressure to book a treatment.
Further reading

From the journal.

Anti-wrinkle vs Botox — is there a difference?

Last updated: 7 May 2026